AME - Biomedical Applications of Spectral Photon Counting CT

X-ray computed tomography (CT) allows scientists and clinicians to non-invasively visualize deep tissue structures within the human body in three-dimensions and at high spatial resolution. However, conventional CT is generally limited to anatomic imaging rather than molecular or functional imaging due to limitations in spectral resolution and soft tissue contrast. Spectral photon-counting computed tomography (PCCT) enables multi-energy X-ray imaging due to advanced, energy-discriminating photon-counting detectors. Material decomposition algorithms combined with spectral PCCT image acquisition transform CT into an anatomical and molecular imaging modality. Students will investigate the transformative imaging capabilities spectral PCCT in high-impact applications that are currently impossible or severely limited with current diagnostic imaging modalities.

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Name of research group, project, or lab
Roeder Lab
Logistics Information:
Project categories
Aerospace and Mechanical Engineering
Electrical Engineering
Student ranks applicable
Sophomore
Junior
Senior
Student qualifications

Engineering (preferred) or science background. Proficiency with Matlab.

Hours per week
2 credits / 6-12 hours
3 credits / 12+ hours
Compensation
Research for Credit
Number of openings
2
Techniques learned

CT image acquisition and material decomposition. Design and preparation of imaging phantoms and preclinical  models.

Project start
Spring 2025
Contact Information:
Mentor
rroeder@nd.edu
Professor
Name of project director or principal investigator
Ryan K. Roeder
Email address of project director or principal investigator
rroeder@nd.edu
2 sp. | 0 appl.
Hours per week
2 credits / 6-12 hours (+1)
2 credits / 6-12 hours3 credits / 12+ hours
Project categories
Aerospace and Mechanical Engineering (+1)
Aerospace and Mechanical EngineeringElectrical Engineering