AME - Nanoparticle Imaging Probes for Contrast-Enhanced CT
X-ray computed tomography (CT) is the most widely used clinical diagnostic imaging modality but is currently limited to anatomic imaging, requiring adjunct modalities for molecular imaging. Therefore, the Roeder lab is working to enable molecular imaging capabilities with CT and spectral photon-counting CT (PCCT) using nanoparticle contrast agents. We are investigating new nanoparticle imaging probes designed for leveraging the capabilities of PCCT, enabling multi-modal imaging, immunotargeting specific cell populations, and monitoring drug delivery. Most recently, we developed nanoparticles to enable non-invasive, longitudinal monitoring of tissue scaffold degradation and drug release by CT.
Name of research group, project, or lab
Roeder Lab