AME - Studying and targeting tumor abnormalities in difficult-to-treat cancers

We have openings for multiple undergraduate researchers on projects related to studying and targeting epigenetic abnormalities in brain and breast cancers. Epigenetic abnormalities influence and can be influenced by other abnormalities in solid tumor microenvironments including mechanics (tissue properties and forces), angiogenesis (abnormal blood vessels), hypoxia (low oxygen content), and metastasis (tumor spread). Undergraduate students will be trained in wet laboratory in vitro techniques such as cell/tissue culture (2-D/3-D cellular models), genomic/epigenomic sequencing (e.g., RNA-seq, ATAC-seq), molecular biology (e.g., PCR, Western Blot), and high-resolution 2-D/3-D imaging, and dry laboratory techniques such as bioinformatics (e.g., using R, Python) and biostatistics. Preference will be given to candidates with prior experience in one or more of these areas. Freshman, sophomores, and juniors from the College of Science and College of Engineering are welcome to apply. Students will be mentored by a full-time Research Scientist working in the lab. 

Name of research group, project, or lab
TIME Lab (Prof. Datta's Lab)
Why join this research group or lab?

The TIME Lab offers a dynamic, enthusiastic, productive, and fun environment for students who are interested in contributing to efforts to cure cancer through non-traditional research. 

Logistics Information:
Project categories
Aerospace and Mechanical Engineering
Biological Sciences
Chemical and Biomolecular Engineering
Chemistry and Biochemistry
Student ranks applicable
First Year
Sophomore
Junior
Student qualifications

Students with prior wet or dry lab research experience - as detailed in the Project Description - will be given priority consideration.

Hours per week
1 credit / 3-6 hours
2 credits / 6-12 hours
3 credits / 12+ hours
Compensation
Research for Credit
Number of openings
4
Techniques learned

Including but not limited to: cell/tissue culture (2-D/3-D cellular models), genomic/epigenomic sequencing (e.g., RNA-seq, ATAC-seq), molecular biology (e.g., PCR, Western Blot),  high-resolution 2-D/3-D imaging, bioinformatics (e.g., using R, Python), biostatistics, oral and written scientific presentation skills. 

Project start
Spring Semester 2025
Contact Information:
Mentor
mdatta@nd.edu
Assistant Professor
Name of project director or principal investigator
Meenal Datta
Email address of project director or principal investigator
mdatta@nd.edu
4 sp. | 19 appl.
Hours per week
1 credit / 3-6 hours (+2)
1 credit / 3-6 hours2 credits / 6-12 hours3 credits / 12+ hours
Project categories
Aerospace and Mechanical Engineering (+3)
Aerospace and Mechanical EngineeringBiological SciencesChemical and Biomolecular EngineeringChemistry and Biochemistry