Quantitative Image Analysis of Colon Tissue

Project Description: 

This undergraduate research project will focus on quantitative analysis of histological images of mouse colon tissue. The student will learn to develop reproducible image-processing and quantification workflows using ImageJ/Fiji. The resulting data will be analyzed across two disease groups for collagen levels with the goal of contributing to a scientific publication. If time permits, the project may also include simple ODE-based modeling of immune-cell interactions to complement the experimental findings.

 

Eligibility: Undergraduate students interested in biomedical research, image analysis, or computational biology; no prior experience required.

 

Objectives:

  • Develop and apply ImageJ/Fiji workflows to quantify colon tissue images and analyze experimental differences.

  • Generate publication-quality results and, if time permits, explore ODE modeling of immune-cell interactions.
Name of research group, project, or lab
CoMMaND Lab
Website
https://commandlab.nd.edu/
Logistics Information:
Project categories
Aerospace and Mechanical Engineering
Student ranks applicable
Junior
Senior
Student qualifications

Undergraduate students interested in biomedical research, image analysis, or computational biology; no prior experience required.

 

Hours per week
2 credits / 6-12 hours
Compensation
Research for Credit
Number of openings
1
Techniques learned

Image processing, Statistical analysis

Project start
08/24/2026
Contact Information:
Mentors
Ahilan Anantha Krishnan
aanantha@nd.edu
Postdoctoral Research Associate
Ahilan Anantha Krishnan
aanantha@nd.edu
Postdoctoral Research Associate
Name of project director or principal investigator
Maria Holland
Email address of project director or principal investigator
maria-holland@nd.edu
1 sp. | 0 appl.
Hours per week
2 credits / 6-12 hours
Project categories
Aerospace and Mechanical Engineering