Spatiotemporal Links: Antibiotic resistance in eDNA & pollution

The Goswami Lab is seeking a student to join a long-term research initiative focused on assessing how heavy metals and organic carbon are distributed across soil and wastewater samples over time and space. Selected student will examine the accumulation and seasonal fluctuations of heavy metals, organic carbon, antibiotic resistance genes (ARGs)  linked to extracellular DNA (eDNA) and a direct study of the history of industrialization and land-use. We expect studying eDNA will allows broad and sensitive detection of bacterial taxa present in an environment, including those not actively growing, making it a powerful tool for biodiversity and ecological studies. Student will be given an opportunity to develop their independent research under PI supervision. For instance, depending on student interests, the research may also connect the structure and function of microbial communities and explore how metal pollution impacts antimicrobial resistance in the environment.

Students interested in interdisciplinary research encompassing environmental chemistry, microbiology, and the environmental legacy of industrialization are encouraged to apply. Key responsibilities include sample preparation, organic carbon metal analysis, DNA extraction and preparing a written report, with opportunities to get involved in manuscript development and poster presentations. Interested students’ can also receive additional training in biostatistical analysis, data visualization using R and data interpretation. This role is designed to help students build essential research skills, including literature review, integration of multidisciplinary approaches, statistical analysis, scientific writing, and effective research communication.

Name of research group, project, or lab
The Goswami Lab
Why join this research group or lab?

Students passionate about the environmental impact of antibiotic resistance will gain hands-on experience in a cutting-edge, impactful research field. Student will directly work on integrating ARG analysis in eDNA with pollution profiling and site industrialization history through spatio-temporal sampling to obtain a holistic view of environmental dimensions of antimicrobial resistance. This approach uncovers causes, persistence, and risks of resistance gene dissemination, guiding science-based interventions for ecosystem and human health protection.

The selected student will gain a unique set of skills that go beyond a single field. Participating in the project will provide an opportunity to learn to handle spatiotemporal data, tracking change in heavy metals and link with ARGs over both space and time, which is a key aspect of real-world environmental research. 

Logistics Information:
Project categories
Biological Sciences
Chemical and Biomolecular Engineering
Chemistry and Biochemistry
Civil & Environmental Engineerng & Earth Sciences
Student ranks applicable
First Year
Sophomore
Junior
Graduate Student
Hours per week
1 credit / 3-6 hours
2 credits / 6-12 hours
Compensation
Research for Credit
Number of openings
1
Techniques learned

Sample Preparation: Hands-on experience in preparing environmental samples for various analytical techniques.

Heavy Metal and Organic Carbon Analysis: Using instruments and methods to measure the concentration of heavy metals in your samples.

Data Analysis & Visualization: Statistical software like R to analyze and interpret complex datasets. This includes training in biostatistical analysis and creating figures to visualize data effectively.

Literature Review: Conduct a comprehensive literature review to understand the current research landscape and frame the project.

Scientific writing and research communication.

Project start
September 15, 2025
Contact Information:
Mentor
agoswam3@nd.edu
Principal Investigator
Name of project director or principal investigator
Anuradha Goswami
Email address of project director or principal investigator
agoswam3@nd.edu
1 sp. | 10 appl.
Hours per week
1 credit / 3-6 hours (+1)
1 credit / 3-6 hours2 credits / 6-12 hours
Project categories
Chemistry and Biochemistry (+3)
Biological SciencesChemical and Biomolecular EngineeringChemistry and BiochemistryCivil & Environmental Engineerng & Earth Sciences